Chimeric mice in which germ cells are derived from the embryonic stem cells are able to transmit the targeted allele. If the chimeras are crossed to the 129 strain from which the embryonic stem ...
1). In a control experiment, we cloned two additional mice from an F1 subcloned cell line (v6.5 sc84). A different targeted line (LJG-13) of 129 strain background gave four embryos which died at ...
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