Dr. Wakil's group also found that the animal ACC enzyme, including that of the human, is present in two isoforms, ACC1 and ACC2. The cDNAs of both isoforms have been cloned and sequenced, and have ...

For some time, our work has focused on understanding the roles of acetyl-CoA carboxylases, ACC1 and ACC2, in the regulation of fatty acid synthesis and oxidation as related to energy homeostasis. Our ...