Metabolic dysfunction-associated steatohepatitis (MASH) is a polygenic disorder influenced by multiple genes, but their ...

The prize was for the determination of the detailed mechanism by which ATP shuttles energy. The enzyme which makes ATP is called ATP synthase, or ATPase, and sits on the mitochondria in animal cells ...

Her studies have changed the traditional view of the spontaneous formation of the proteasomal ATPase ring, via revealing conserved novel assembly chaperones for regulating assembly of the ...

Metabolic dysfunction-associated steatohepatitis (MASH) is a liver disease that progresses without symptoms and is associated ...

Nonetheless, all remodelers contain a subunit with a conserved ATPase domain. In addition to the conserved ATPase, each remodeler complex also possesses unique proteins that specialize it for its ...

Recent studies indicate that the dysfunction of sarco/ER calcium ATPase (SERCA2), which regulates Ca 2+ transport to the ER, can also induce ER stress, contributing to MASH. In addition to SERCA2 ...