they transitioned the astrocytes to a pathogenic state by adding microglia-derived cytokines, which are the molecular cues that induce reactivity in neurodegenerative diseases. 2 Using this system to ...

leading to the activation of A1 astrocytes and M1 microglia and elevated neuroinflammatory cytokines. The disruption of this crosstalk between IL-3 and IL-3Rα induces lipid metabolic ...

Astrocytes, on the other hand, support metabolic functions, neurotransmitter regulation, and immune responses by releasing ...