A research team led by Prof. JIANG Yanyi from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences, ...

Figure 8: Regulation of ALDH3A1 and NECTIN4 by p53. Researchers Jessica J. Miciak, Lucy Petrova, Rhythm Sajwan, Aditya Pandya, Mikayla Deckard, Andrew J. Munoz, and Fred Bunz from the Sidney ...

Further experiments revealed that TP63, an oncogene, acts as a "master switch" for ALDH3A1. It directly activates the ALDH3A1 gene, triggering the protective mechanism. When the researchers turned ...

In this study, the researchers found that the protein ALDH3A1, known for its role in detoxifying harmful substances in the body, is overactive in SCC cells. This protein acts as an "antioxidant ...