Recent research has focused on understanding the biosynthesis of these antifungal compounds, their mechanisms of action, and how they can be effectively utilized in treating fungal infections.

An often-overlooked mechanism of gene regulation may be involved in the failure of antifungal drugs in the clinic. This has been discovered by a German-Austrian research team led by the Leibniz ...

Importance of RNA modifications for the development of resistance in fungi raises hope for more effective treatment of fungal ...

Another issue is that antifungal drug development takes a long ... Over the last 25 years, a compound with a novel mechanism ...

An often-overlooked mechanism of gene regulation may be involved in the failure of antifungal drugs in the clinic, claims a German-Austrian research team led by the Leibniz Institute for Natural ...

These compounds have shown better inhibitory effects than traditional antifungal agents like ketoconazole ... providing insights into their mechanisms of action[5]. Another significant aspect ...

See the article: Improving the production of micafungin precursor FR901379 in Coleophoma empetri using heavy-ion irradiation and its mechanism analysis ...

"For decades, clinicians have relied on a handful of antifungal classes, with few mechanisms of action and significant limitations due to spectrum of activity, drug toxicities, or drug-drug ...

Agrichemical antifungal use is leading to fungi that can evolve resistance to novel drugs faster - even those not even on the market yet ...

Olorofim (F901318) is the first in a new class of orotomide antifungal agents intended ... dihydroorotate dehydrogenase (DHODH), a different mechanism from that of the currently marketed therapies ...

These methods have been adopted as part of the CLSI Reference Methods for Antifungal Susceptibility Testing. Strong support for these research efforts are drawn from different sources including the ...