Surrogate End Points for Overall Survival in Neoadjuvant Randomized Clinical Trials for Early Breast Cancer Twenty-eight patients underwent apheresis and received CAR T cells. Sixteen and 12 patients ...

Some recent studies have suggested that T cells can become activated via recognition ... unknown. B cells contribute to the rejection of skin allografts by presenting donor antigens to T cells ...

Induces potent and long-lasting immune responses to defined antigens or whole pathogens (particles), mainly through the ...

Researchers found that bioengineered CAR-T cells when mixed with other immune cells can "donate" proteins, suggesting ...

Engineered immune cells called CAR-T cells are used in the treatment of cancer. Researchers from Uppsala University have now ...

T-cells from the liver and lymph nodes show promising potential for future treatments of liver cancer, according to a new ...

Chimeric antigen receptor-T (CAR-T) cell therapy, initially successful in hematologic malignancies, presents a promising avenue for treating solid tumors, including CRC. This review explores the ...

A study shares new insights into how two of the most common types of chimeric antigen receptor ... beyond B cell malignancies. "We looked at two different types of CAR T cells.

Transplanted organs express donor MHC molecules, resulting in 2 pathways of antigen recognition (allorecognition ... antigen and is delivered via the T-cell receptor. The second signal ...

View Full Profile. Learn about our Editorial Policies. Chimeric antigen receptor (CAR) T cell therapy leverages patients’ immune systems to fight cancer. This immunotherapy greatly expanded treatment ...