The immunomodulatory character of bacterial CpG DNA is well known. A report in a recent issue of Nature pinpoints a Toll-like receptor as the cellular accomplice in this innate immune reaction.

A new study has been published in Nature Communications, presenting the first comprehensive atlas of allele-specific DNA ...

which occurs in DNA at so-called "CpG" positions, where C is followed by the base guanine (G). Such tagging, commonly seen across the genome, plays a fundamental role in controlling the expression ...

A comprehensive atlas maps DNA methylation across 39 human cell types, revealing a complex landscape of epigenetic regulation.

Transposons, so-called jumping genes, are a threat to genomes, so plants work hard to prevent them from mobilizing and ...

The roles and targets of DNA methylation vary among the kingdoms of organisms. As previously noted, among Animalia, mammals tend to have fairly globally distributed CpG methylation patterns.

Researchers have developed a comprehensive atlas that maps DNA methylation—a critical chemical modification governing gene ...