At any one time, a cell is receiving and responding to numerous signals, and multiple signal transduction pathways are operating in its cytoplasm. Many points of intersection exist among these ...

If there is one thing that is known about the mechanisms that govern signal transduction, it's that not very much is known. When signaling molecules bind to a cellular receptor, they set off a chain ...

Researchers have identified a method to enhance the effectiveness of a promising cancer treatment. They found that modifying ...

A research team led by Dr. Tetsuya Muramoto from the Faculty of Science at Toho University has demonstrated the mechanisms by which periodic chemical signal frequencies in cells regulate gene ...

Biochimica et Biophysica Acta 1788, 779–789 (2009). Juliano, R. L. Signal transduction by cell adhesion receptors and the cytoskeleton: Functions of integrins, cadherins, selectins, and ...

Members of the program engage in research aimed at obtaining a mechanistic understanding of signal transduction and cellular regulation, which includes cellular signaling pathways and downstream ...

Ad5 vectors transduce a wide range of cell types. They utilize the Coxsackie-Adenovirus Receptor (CAR) to enter cells. Transduction efficiency is related to the level of CAR expression on the cell ...

Saltiel, department of signal transduction, Parke-Davis, Ann Arbor, Mich. The chemical signals triggering cellular growth resemble multiple pathways more closely than a single trail. Consequently, ...

The findings highlight the significance of frequency-selective cellular responses in developmental biology, providing valuable insights into the intercellular signal transduction mechanisms.