The effect of CpG DNA is, thus, almost identical to that of the more classical inducers of the innate immune system, for example, LPS, peptidoglycan and other components of bacterial cell walls ...
which occurs in DNA at so-called "CpG" positions, where C is followed by the base guanine (G). Such tagging, commonly seen across the genome, plays a fundamental role in controlling the expression ...
The roles and targets of DNA methylation vary among the kingdoms of organisms. As previously noted, among Animalia, mammals tend to have fairly globally distributed CpG methylation patterns.
A new study has been published in Nature Communications, presenting the first comprehensive atlas of allele-specific DNA ...
A comprehensive atlas maps DNA methylation across 39 human cell types, revealing a complex landscape of epigenetic regulation.
DNA methylation, a key epigenetic alteration ... Similarly, nine differentially methylated CpG sites (DMSs) were identified in the plasma cohort, of which only two were hypermethylated in lung ...