The process of drug disposition can be divided into four parts — absorption, distribution, metabolism and excretion ... transporter B1 (ABCB1) and cytochrome P450 3A4 isoform (CYP3A4), are ...
Attention should be paid to the relative importance of the warfarin cytochrome P450 (CYP) metabolic pathways. Warfarin is a racemic mixture of its R-isomer (less potent) and S-isomer (more potent).
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