and other adaptor complexes bind desmosomes to intermediate filaments. Both of these types of junctional complexes provide cells and tissues with mechanical support, and they additionally recruit ...

Cells hold on to each other through junctions that serve to connect the neighboring cells. At least three types of junctions are known: tight junctions, adherens junctions, and desmosomes.

Adherens junctions (red dots) join the actin filaments of neighboring cells together. Desmosomes are even stronger connections that join the intermediate filaments of neighboring cells.

in which autoantibodies react with the cell–cell adhesion structures, desmosomes, causing blisters and erosions on the oral mucosa and skin. Pemphigus is divided into two major subtypes ...