To determine whether the endothelium is activated in this disease, we studied the number, origin, and surface phenotype of circulating endothelial cells in patients with sickle cell anemia.

Sickle cell disease is associated with endothelial dysfunction (the cascading effects of which result in elevation of d-dimer levels), and endothelial dysfunction is another hypothesized ...

CSL Behring’s dedication of its R&D activities to develop novel therapies for sickle ... comprising cell–cell interactions and increased endothelial adhesiveness, endothelial dysfunction ...