The Falke group is currently investigating the molecular mechanisms of on-off switching of components within the chemosensory array, especially the mechanisms by which transmembrane receptors bind ...

For example, prokaryotic organisms have sensors ... When a signaling molecule joins with an appropriate receptor on a cell surface, this binding triggers a chain of events that not only carries ...

Each of these cells also has ion channel receptors clustered on a particular part of its surface. For example, the receptors that respond to chemical signals are generally located at synapses ...

Almost 35% of drugs approved by the Food and Drug Administration work by targeting G protein-coupled receptors (GPCRs), proteins embedded in cell membranes that allow cells to communicate with ...

Engineered immune cells called CAR-T cells are used in the treatment of cancer. Researchers from Uppsala University have now ...