A new clinical study shows that an inhibitor of Fas ligand (FasL), also called CD95 ligand (CD95L), led to a faster recovery of COVID-19 patients and reduced mortality. On average, it took eight ...

The cell-extrinsic pathway is initiated by ligand engagement of death receptors, such as FAS (also known as CD95) on the cell surface. Initiation of the cell-intrinsic pathway involves the ...

A new clinical study shows that an inhibitor of Fas ligand (FasL), also called CD95 ligand (CD95L), led to a faster recovery of COVID-19 patients and reduced mortality. On average, it took eight ...

FasL expressed on tissues would engage the Fas receptor expressed on the surfaces of immune cells, causing them to undergo programmed cell death (Fig. 1). The idea that FasL (also known as CD95 ...