Approximately 40–50% of liver transplants in the US are the result of HCV infection. Six major HCV genotypes (HCV1–6) have been identified, which vary in their geographic distribution and ...

Across genotypes, only a few regimens are recommended ... an analysis of people receiving HCV care through the US medical system for military veterans – approximately 187,000 veterans diagnosed ...

Additional virological tools including a broad array of infectious clones covering all HCV genotypes are needed to effectively test vaccine-induced immunity in vitroand in vivo. Integration of ...

Nucleotide analogs are already in the active form. Because the NS5B target is highly conserved between HCV genotypes, polymerase inhibitors usually have pangenotypic activity (Fig. 1). PSI-938 is ...