To help predict the efficacy of our vaccine candidate against true heterologous viral strains, we performed a stringent vaccination and heterologous challenge test to mimic the most probable ...

More information: Chunhong Dong et al, Enhancing cross-protection against influenza by heterologous sequential immunization with mRNA LNP and protein nanoparticle vaccines, Nature Communications ...

The study results were published in the Lancet journal. "These data collectively show that the heterologous vaccine based on rAd26-S and rAd5-S is safe, well tolerated, and does not cause serious ...

To date, the data indicate that the most efficacious vaccine strategy might be a heterologous combination of intranasal and systemic vaccination, since each delivers different aspects of protection.

The company is also exploring the possibility of using their vaccine as a heterologous booster dose. CanSinoBIO aims to get the inhaled version available and approved for use in the market as soon ...