Saha, K. & Jaenisch, R. Technical challenges in using human induced pluripotent stem cells to model disease. Cell Stem Cell 5, 584–595 (2009). Takahashi, K. & Yamanaka, S. Induction of ...

A team of bioengineers at de-extinction company Colossal Biosciences has announced that they created induced pluripotent ... mice and human cells. They also added so-called Yamanaka factors ...

In 2006, Kazutoshi Takahashi and Shinya Yamanaka ... somatic cells into a pluripotent state via the expression of transcription factors Oct4, Sox2, Klf4, and c-Myc. 1 Now, researchers can ...

World-renowned stem cell scientists will gather in Kyoto, Japan for the International Society for Stem Cell Research (ISSCR) ...

Stem cell research is still a new field within biology. Many big advances, like the discovery of human embryonic ... led by Shinya Yamanaka showed in 2006 that specialized mouse cells can be ...

Today researchers are able to reprogram cells that are obtained from adult tissues to turn back in development into cells that resemble embryonic stem cells. These cells are called induced pluripotent ...

Induced pluripotent stem cells ... circuit for cell-based delivery of biologic drugs at controlled times of day. Optimized lentiviral transduction enhances gene delivery in human iPSC-derived ...

His resignation will allow Yamanaka, 59, to spend more time researching induced pluripotent stem (iPS) cells, which can be reprogrammed into becoming different types of cells in the body. “ ...

CRISPR’ing human iPSCs allows researchers to manipulate genes to study their functions in the context of specific diseases, or to correct genetic defects in patient cells. One challenge that seamless ...

The main focus in the lab is on the biology and application of human embryonic stem (ES) and human induced pluripotent (iPS) cells. Pluripotent stem cells can provide a truly unlimited source for ...

The research involves induced ... cells back into a pluripotent state, work that was recognized with a Nobel Prize to the ...