Subtle signs of neurodegeneration can be detected in blood, CSF, and neuroimaging, up to 20 years before the motor symptoms ...

Symptoms of Huntington's disease appear late in life. Research reveals how DNA repeats grow toxic over time, explaining the ...

Huntington's disease is a hereditary disorder caused by a genetic mutation in the HTT gene, leading to progressive brain cell damage, affecting movement, cognition, and behavior, with no current cure.

Approximately 23 years before a clinical diagnosis, CSF analysis showed very early signs of neurodegeneration with elevated ...

A new study of nerve cells affected by Huntington’s disease (HD) reveals that the disease-causing gene slowly expands over ...

Researchers have made a major breakthrough in our understanding of Huntington's disease. This genetic disorder has long been ...

A highly-anticipated scientific paper has landed! This new work challenges current theories in Huntington’s disease research, ...

Could viral infections play a role in Huntington's disease? Research suggests Apolipoprotein B mRNA editing catalytic ...

A recent study published in Cell reveals that the repeated DNA sequence that leads to Huntington’s disease (HD) expands ...

For some reason McCarroll and his team still doesn't fully understand, in people with Huntington's Disease, the repair ...

Huntington's disease (HD) is an inherited neurodegenerative disease caused by an abnormal expansion of a CAG repeat in the huntingtin ( HTT) gene. The primary genetic determinant of the age at ...

in people with Huntington's Disease, the repair mechanism that tries to fix these broken zippers on their Huntingtin gene end up adding extra CAG repeats. It's like one side of the zipper keeps ...