Subtle signs of neurodegeneration can be detected in blood, CSF, and neuroimaging, up to 20 years before the motor symptoms ...

For many people, the symptoms of Huntington's disease will not begin to show for decades. The genetic disorder is incurable but it is not uncommon for sufferers to reach middle-age before the ...

CAMBRIDGE, Massachusetts ‒ For decades it's been one of the defining mysteries of Huntington's disease. Why does the terrible devastation of mind and body start earlier in some people who ...

Scientists are unraveling the mystery of what triggers Huntington’s disease, a devastating and fatal hereditary disorder that strikes in the prime of life, causing nerve cells in parts of the ...

Surprise Finding Sheds Light on What Causes Huntington's Disease, a Devastating Fatal Brain Disorder Scientists are unraveling the mystery of what triggers Huntington’s disease, a devastating ...

This type of "somatic expansion" occurs in only the specific types of brain cells that later die in Huntington's disease. Only once a cell's DNA expansion reaches a threshold number of CAGs ...

A new study of nerve cells affected by Huntington’s disease (HD) reveals that the disease-causing gene slowly expands over time but doesn't start causing harm until it hits a toxic threshold ...

Nov. 13, 2024 — The Huntington's disease (HD) mutation eventually causes a fatal brain disease in adulthood, but a new study finds that early in life, children with the HD mutation have bigger ...

WASHINGTON — Scientists are unraveling the mystery of what triggers Huntington’s disease, a devastating and fatal hereditary disorder that strikes in the prime of life, causing nerve cells in ...