In a new study reported in Science Advances, scientists analyzed MRI data stored at the UK Biobank and identified seven genes ...

We have developed a series of targeted mice expressing frontotemporal-dementia-causing mutations in the humanized MAPT gene to investigate the earliest stages of tauopathy." Tau ...

The MHC region, which has four million base pairs on chromosome 6, a 0.7-million-base-pair locus on chromosome 4 encoding an enzyme for drug metabolism, and the 1.5-million-base-pair MAPT gene on ...

Scientists have identified the 1N4R tau isoform as a key driver of Alzheimer’s disease, paving the way for potential new ...

Dr Buchholz and Dr Zempel’s team have used state-of-the-art techniques such as CRISPR/Cas9 gene editing and live ... 1N4R confers vulnerability of MAPT knockout human iPSC-derived neurons ...

For those who don't qualify for long-term care insurance or can't afford it, the Medicaid Asset Protection Trust ("MAPT") can protect your assets from the high cost of long-term care in your home ...

Researchers at the University of Cologne have identified a specific form of the tau protein that is responsible for mediating the toxicity of harmful protein clumps in human neurons and thus ...