Hosted on MSN11mon
Genetic association study opens up new treatment avenues for Pick's disease, a rare form of early-onset dementiaResearchers at Mayo Clinic in Florida, University College London in England and collaborators worldwide have established the Pick's Disease International Consortium to study a specific MAPT gene ...
Hosted on MSN2mon
Genetically modified mice hint at tau hyperphosphorylation's early role in neurodegenerative diseasesWe have developed a series of targeted mice expressing frontotemporal-dementia-causing mutations in the humanized MAPT gene to investigate the earliest stages of tauopathy." Tau ...
The study was published in the Alzheimer's & Dementia journal under the title "The TAU isoform 1N4R confers vulnerability of MAPT knockout ... such as CRISPR/Cas9 gene editing and live-cell ...
Results that may be inaccessible to you are currently showing.
Hide inaccessible results
Feedback