Deciding to start a family is a big decision for any couple, but it’s even more nerve-wracking when the mom-to-be has a ...

Marfan syndrome is a genetic condition involving the body's connective tissue. Connective tissue gives structure and support to all parts of the body, including the skin, bones, blood vessels, and ...

AIM To examine evolution of the physical characteristics of Marfan’s syndrome throughout childhood. METHODS 40 children were ascertained during the development of a regional register for Marfan’s ...

After swimming, he had developed sudden chest and back pain. He showed physical features of Marfan syndrome such as an increased arm span to height ratio greater than 1.05; additionally, arms and legs ...

The standard treatment for the connective tissue disorder Marfan's syndrome (MFS) is β-blockade, aimed at reducing aortic wall stress. Angiotensin II type 1 and 2 receptors (AT 1 and AT 2 ...

Fibrillin-1 mutations have also been found in patients who do not fulfil clinical criteria for the diagnosis of Marfan syndrome, but have related disorders of connective tissue, such as isolated ...

Objective: To report a family with Marfan’s syndrome in whom a myopathy was associated with respiratory failure; muscle biopsies from affected individuals were examined to determine whether there were ...

In light of the effects that PP2A can exert on the mTOR pathway, we hypothesized that PP2A activation by small-molecule activators of PP2A could mitigate AA progression in Marfan syndrome (MFS). Two ...

Marfan syndrome is a genetic condition involving the body's connective tissue. Connective tissue gives structure and support to all parts of the body, including the skin, bones, blood vessels, and ...

Marfan syndrome is a connective tissue disorder that causes the tissue to stretch and eventually tear. If the disorder is not detected early enough, the tissue that forms the aorta (the heart’s major ...