A significant subset of MASLD patients progresses to metabolic dysfunction-associated steatohepatitis (MASH), liver fibrosis, and even hepatocellular carcinoma (HCC), yet no universally approved ...

FibroScan overestimated advanced fibrosis and cirrhosis in patients with class 3 obesity and metabolic dysfunction-associated steatotic liver disease.

(Journal of Hepatology) Meanwhile, modeling data predicted that by 2050 the prevalence of MASLD in the U.S. population ... for hepatocellular carcinoma (HCC) surveillance in patients with cirrhosis.

More than 11% of US adolescents had suspected metabolic dysfunction–associated steatotic liver disease (MASLD), and 77.2% with elevated alanine aminotransferase (ALT) levels met the criteria for ...

A study published in Nature Aging has revealed a promising new drug candidate that may help combat metabolic dysfunction-associated steatotic liver disease (MASLD), a chronic liver condition that ...

Two in 5 US adults (approximately 122 million) will have metabolic dysfunction–associated steatotic liver disease (MASLD) by 2050, with a concurrent increase in liver cancer, cirrhosis ...

Through the PLANet and ELEGANCE programmes, Prof Chow and his team discovered that dysregulated bile acid is a key risk factor for HCC, particularly in MASLD HCC. This dysregulation is linked to ...

"This study provides evidence that MASLD originates in the womb, influenced at least in part by a mother's high-fat diet," Friedman said. "The discovery of elevated bile acid levels in fetuses may ...

Dr. Sobia Laique, chair of the MASLD Task Force at Cleveland Clinic, introduces spacial genomics, which provides a high-resolution view of cellular heterogeneity and spacial organization ...