During prophase, the replicated pairs of chromosomes ... called the mitotic spindle also forms from long proteins called microtubules on each side, or pole, of the cell. During prometaphase ...

Mitosis orchestrates eukaryotic cell division, maintaining genetic fidelity and playing a key role in development, tissue homeostasis, and cancer progression.

It is now well-established that spindles are bipolar arrays of microtubules composed of tubulin (Figure 5) and that the centrosomes nucleate the growth of the spindle microtubules. During mitosis ...