These may be endured by patients with cancer but those with non-malignant ... USA), a 50 kDa aptamer that binds to PDGF-B. A Phase I escalating dose trial enrolled 57 patients with advanced ...

There is therefore an urgent need for the development and testing of novel agents targeting pathways thought to be involved in the pathogenesis of breast cancer ... 2 and 3, PDGF receptors ...

Brain tumors remain the most common cause of death from childhood cancer. Paediatric high-grade gliomas (pHGG) in particular are a mostly fatal disease group with a median survival time of less than ...