Monoallelic loss of PTEN and ARID1A is identified in normal colonic epithelium. The resulting haploinsufficient phenotypes ...
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Q&A: Researchers discuss lipid nanoparticle therapy to stop tumor growth and restore tumor suppressionWe hypothesized that using mRNA and siRNA simultaneously could restore tumor suppressors and inhibit drivers of tumor growth, such as PTEN and AR ... select specific pathways to target that ...
We used lipid nanoparticles to deliver mRNA and siRNA to human PCa cells to evaluate our technique's ability to both restore the lost PTEN and silence ... select specific pathways to target ...
The research indicated that deguelin's ability to enhance PTEN and KLF4 expression could ... forming new tumors. Signaling Pathways: Complex networks of molecules in a cell that work together ...
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