The EMBO Journal6d
Haploinsufficient phenotypes promote selection of PTEN and ARID1A-deficient clones in human colon
Monoallelic loss of PTEN and ARID1A is identified in normal colonic epithelium. The resulting haploinsufficient phenotypes ...
Targeted cancer cell therapy may slow endometrial cancer
"ERBB2 and PTEN are a part of different signaling pathways, but we believe they have a correlation in endometrial cancer," ...
Phys.org1mon
Q&A: Researchers discuss lipid nanoparticle therapy to stop tumor growth and restore tumor suppression
We hypothesized that using mRNA and siRNA simultaneously could restore tumor suppressors and inhibit drivers of tumor growth, such as PTEN and AR ... select specific pathways to target that ...
Nature15d
Deguelin's Role in Cancer Cell Proliferation and Apoptosis
The research indicated that deguelin's ability to enhance PTEN and KLF4 expression could ... forming new tumors. Signaling Pathways: Complex networks of molecules in a cell that work together ...