they use different programming languages and have different pinouts. Spec-wise, the Pico 2 W boasts dual Arm Cortex-M33 or dual Hazard3 RISC-V processor running at 150MHz, 520KB of on-chip SRAM ...

so you don’t need to restrict yourself to the “official” Pico-W, so long as you have working networking, Wi-Fi or otherwise. Integration is provided by the arduino-home-assistant library ...