Personalised use of repurposed non-anticancer drugs in colorectal cancer based on up-regulated signalling pathways: A real world cohort feasibility study. This is an ASCO Meeting Abstract from the ...

We have found that PVA replication is dependent on phosphorylation of PVA CP by protein kinase CK2 and a functional HSP70/HSP40 host chaperon pathway targeting CP to proteasomal degradation [2]. We ...