Was this a function of differences in receptor primary sequence, their locations in the cell, or, possibly, the specificity of the protein kinase domain of the receptor? As we mapped and mutated ...

Figure 2: Mitogen-activated protein kinase scaffold proteins in immune ... using well-defined protein domains, such as leucine zippers, to facilitate the interaction. This method can be used ...

A quantitative protein interaction network for the ErbB ... Structure of the epidermal growth factor receptor kinase domain alone and in complex with a 4-anilinoquinazoline inhibitor.

LRRK2 has two enzyme "domains"—a kinase and GTPase domain ... and guanosine diphosphate (GDP) in the protein regulation process. Xiong has identified a key regulator for GTPase function called ...

Trl1 (827-aa) and AtRNL (1104-aa) are homologous proteins composed of separable healing and ... mutations in the active sites of the CPD, kinase, and ligase domains are lethal in vivo; and (iii) phage ...