San Francisco 49ers tight end George Kittle catches a touchdown pass from Tampa Bay Buccaneers quarterback Baker Mayfield in the 2025 NFL Pro Bowl flag football game. San Francisco 49ers fullback ...

San Francisco 49ers defensive back Deommodore Lenoir takes fans inside his biggest career moments in this episode of "Inside the Play" presented by Microsoft Surface Pro.

Watch the top defensive plays from Wild Card Weekend during the 2024 NFL season. Watch highlights from the Wild Card Weekend matchup between the Minnesota Vikings and the Los Angeles Rams during ...

ESPN analyst Dan Orlovsky urges the San Francisco 49ers to "immediately call" the Los Angeles Rams and inquire about trading ...

The recent meetings have been all San Francisco. The 49ers have won the last three, eliminating Dallas from the playoffs in one-touchdown games in 2021 and 2022 and blowing out the Cowboys 42-10 ...

Watch all of the highlights from the Detroit Lions' 40-34 Week 17 victory over the San Francisco 49ers. Watch Detroit Lions quarterback Jared Goff connect with San Francisco 49ers fullback Kyle ...

Watch all of the highlights from the game between the New Orleans Saints and the San Francisco 49ers in Week 2 of the 2024 NFL Preseason. Watch highlights of New Orleans Saints quarterback Spencer ...

The San Francisco 49ers are widely expected to strengthen their offensive or defensive line in the 2025 NFL Draft—two ...

The San Francisco 49ers send wide receiver Deebo Samuel, running back Jordan Mason, and multiple draft picks to the ...

San Francisco must improve their interior defensive line, and Dallas Cowboys defensive tackle Osa Odighizuwa provides an ...

Watch highlights from the New Orleans Saints vs. San Francisco 49ers game in Week 10 of the 2014 NFL season as the teams needed overtime to settle the score. In overtime Saints quarterback Drew ...