Jiangsu Hengrui Medicine Co. Ltd. and Shanghai Hengrui Pharmaceutical Co. Ltd. have disclosed Toll-like receptor 7 (TLR7) and/or TLR8 and/or TLR9 antagonists reported to be useful for the treatment of ...
News Medical on MSN2mon
Complex interactions between nucleic acid sensors and enzymes in immune cells explainedA denosine deaminase 2 (ADA2) has been identified as a regulator of toll-like receptor 9 (TLR9) activation in response to ...
TLR7 and TLR9 are also thought to be involved in B-cell-mediated production of autoantibodies specific to nucleic acids, thereby triggering and then promoting SLE. Barrat et al. have described ...
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