The adaptors activate other relay proteins inside the cell, and this chain of protein-protein interactions creates a signal transduction pathway that links an activated receptor to its response.

The discovery of microbial-sensing proteins called Toll-like receptors is transforming our understanding of the body’s response to infection. Aa Aa Aa A diverse range of microbes, including ...

EMCV: Encephalomyocarditis virus; HCMV: Human CMV: MCMV: Mouse CMV; MMTV: Mouse mammary tumor virus; pDC: Plasmacytoid dendritic cell; PTV: Punta Toro virus; SARS-CoV ...

Dr. Ma adds, "Our results show that BB1 prevented the TNF-α increase in intestinal tight junction permeability via a toll-like receptor (TLR)-2 signal transduction pathway inhibition of NF-kB p50 ...