The digestion of alcohol happens in two steps - first, the ethanol is converted to acetaldehyde, and then the Aldehyde dehydrogenase (ALDH) enzyme converts the acetaldehyde to acetate. The ...
View Full Profile. Learn about our Editorial Policies. Alcohol is broken down in the human body by two main enzymes, alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH). Mutations in these ...
Testing ALDH was the next step. We set up an inhibition assay in test tubes. In the assay, we measured how fast the enzyme ALDH breaks down acetaldehyde. Then, we added the suspected inhibitors ...
Another enzyme, aldehyde dehydrogenase (ALDH), then turns acetaldehyde into non-toxic acetic acid (vinegar). Older adults have less than average ALDH, which explains why our response to alcohol ...