The table below is a review of notable updates that occurred in January 2025 for investigational products in development.

We show here that Fas kills activated primary T cells efficiently in the absence of active caspases ... Jurkat T cells, the kinase receptor-interacting protein (RIP) was identified as a crucial ...

AF6 denotes afadin, GAP GTPase-activating protein, GEF guanine exchange factor, MEK mitogen-activated protein kinase kinase ... displace PI3K from active KRAS. In addition, active KRAS may ...

A-kinase anchoring proteins (AKAPs) target PKA to specific substrates and ... Besides the Gs/AC/cAMP pathway, active EP2 and EP4 receptors trigger multiple signaling pathways, which can counteract the ...

Physical activity is not only important for fitness, but also for health. This is confirmed by a new study conducted under the direction of Prof. Dr ...

Pharmaceutical ads are difficult to avoid in American television programming and a growing number of them promote a class of ...

New Delhi: Pharmaceutical major Dr Reddy's has got approval from the Subject Expert Committee (SEC) functional under the ...

Chronic lymphocytic leukemia (CLL) is a B-cell malignancy, with disease progression ranging from slow and indolent to ...

A postdoctoral researcher in the department of physics and biology at Princeton University gave a guest lecture about a ...

The study explores molecular mechanisms underlying synaptic plasticity - the strengthening or weakening of neuronal connections that enable learning and memory.

Chief R&D and commercial officer Najat Khan, PhD, tells GEN Edge the company aims to improve design of studies, accelerate enrollment, and enhance evidence generation.