In a breakthrough for influenza research, scientists have discovered immune cells that can recognize influenza (flu) viruses ...

Scientists have progressed from merely provoking an anti-cancer immune response to designing it ...

Induces potent and long-lasting immune responses to defined antigens or whole pathogens (particles), mainly through the ...

Chimeric antigen receptor-T (CAR-T) cell therapy, initially successful in hematologic malignancies, presents a promising avenue for treating solid tumors, including CRC. This review explores the ...

we show the evolution of the tumor in the case with efficient T-cells and NAFs without CAFs (Fig. Sup. 1H). We also obtain different configurations by assuming deformed domains in order to study the ...

Pathogen-fighting immune cells called tissue-resident memory CD8 T cells (TRM cells) go through a surprising transformation -- and relocation -- as they fight infections in the small intestine.

However, an integrated understanding of iNKT cell activation, the molecular interactions governing agonist presentation and recognition ... including secondary activation of regulatory T and B cells, ...

CD19-directed chimeric antigen receptor (CAR) T-cell therapy, originally developed for haematological malignancies, has recently emerged as a promising therapy for patients with autoimmune diseases.

Kathryn Senior reports. Chimeric antigen receptor (CAR) T-cell therapies have proved effective in several haematological cancers including B-cell acute lymphoblastic leukaemia, diffuse large B-cell ...

Communication between MKs and other immune cells is a key aspect of their immune function. MKs secrete cytokines that influence B cell ... pathogen recognition, phagocytosis, and antigen presentation.

The persistence and recurrence of inflammatory diseases can be attributed to clonally expanded antigen-specific ... reported that granzyme B (GZMB)-expressing CD8+ T-cells have induce type 1 ...