Increased activity of the ryanodine receptor Ca release channel was found in atrial myocytes of patients with poAF and a novel mouse model of poAF. Our data suggest that enhanced RyR2 activity is ...

In addition, it is reported to activate a depolarizing inward sodium current that is sensitive to the calcium channel blocker (CCB) nifedipine in isolated human atrial myocytes. It has been ...

As expected, application of I Kur blocker produced pronounced action potential duration (APD) prolongation in atrial myocytes. Furthermore, combined multiple K +-channel block that mimicked the ...

Hydroxychloroquine permeates myocytes and induces an acquired lysosomal ... a finding suggestive of left atrial contractile dysfunction. A diminutive A wave was observed on transmitral Doppler ...

Right atrial drivers were recorded in 20% of the cases. Fibrosis represents the most important structural remodeling that promotes AF. Fibrosis can be reactive (located at the interstitial space) or ...

Due to concern for pulmonary hypertension (PAH), right heart catheterisation was scheduled for further haemodynamic evaluation, which revealed right atrial pressure 14 ... of phospholipases inside ...

Atrial fibrillation (AFib) is the most common form of irregular heartbeat (arrhythmia). People with AFib have many treatment options, including medications and medical procedures. However ...

Atrial fibrillation is a cardiac arrhythmia in which the upper chambers of the heart the atria beat irregularly and, often, rapidly. The condition occurs as a consequence of uncoordinated ...

The safety of abelacimab as compared with a direct oral anticoagulant in patients with atrial fibrillation is unknown. Patients with atrial fibrillation and a moderate-to-high risk of stroke were ...

Binge drinking and possibly, moderate alcohol intake, may trigger atrial fibrillation. Caffeine intake does not appear to be a trigger; although, some doctors still recommend that patients with atrial ...

Harbaugh has what's called an atrial flutter, which is a type of arrhythmia that causes the heart to beat at an abnormally high rate. The coach departed the Chargers' Week 6 game against the ...