Multiple forms of double-stranded RNA (blue, magenta, orange structures) cross cell membranes with the help of a conserved ...

UMD researchers have discovered key mechanisms in gene regulation that could improve the design of RNA-based medicines.

Although RNA is a single-stranded molecule, researchers soon discovered that it can form double-stranded structures, which are important to its function. In 1956, Alexander Rich—an X-ray ...

There are many molecules with therapeutic potential, but it can be a challenge to deliver them to the right places at the ...

Specifically, one strand of a double-stranded siRNA molecule can be incorporated into a complex called RISC. This RNA-containing complex can then inhibit transcription of an mRNA molecule that has ...

The system requires the use of Biosynthesis’s Blood RNA Preservative Tubes for blood collection and RNA stabilization, followed by RNA purification using spin column chromatography based on ...

Multiple forms of double-stranded RNA (blue, magenta, orange structures) cross cell membranes with the help of a conserved protein located in novel sites (colored by depth) throughout the ...

as demonstrated by the recent successes of RNA vaccines and double-stranded RNA (dsRNA) therapies. But while health care providers can now successfully develop drugs that use dsRNA to accurately ...

Comparison of a single-stranded RNA and a double-stranded DNA with their corresponding nucleobases (Image: Wikimedia Commons, CC SA 3.0) Transfer RNA (tRNA) molecules are responsible for delivering ...

RNA-based medicines are one of the most promising ways to fight human disease, as demonstrated by the recent successes of RNA ...