In a new study, researchers have determined that a protein called NF-kB c-Rel can intensify the symptoms of psoriasis when activated by signals from the body's immune system. Understanding how 'c-Rel' ...

The activation of these MAPKs leads to some important transcription factor activations, such as CREB, AP1. These transcription factors cooperate with NF-κB to promote the induction of pro-inflammatory ...

By interacting with adaptor protein TNF receptor-associated factor 2 (TRAF2), IRE1α can also activate c-Jun N-terminal kinase (JNK) and nuclear factor κB (NF-κB) pathways, thereby modulating ...

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