A single myosin filament connects to two actin filaments on either side, forming a single unit of muscle tissue known as a sarcomere. Intercalated discs connect cardiac muscle cells. Gap junctions ...

Numerous motor and structural proteins compose a highly ordered structure known as the sarcomere, the basic unit of muscle contraction in heart and skeletal muscles. Sarcomeric myosin heavy chain ...

Russell Alan J, the Chief Scientific Officer of Edgewise Therapeutics , Inc. (NASDAQ:EWTX), executed a series of stock transactions recently, as detailed in a recent SEC filing. On February 5 and 6, ...

Kevin Koch, the President and CEO of Edgewise Therapeutics , Inc. (NASDAQ:EWTX), a biotechnology company with a market capitalization of $2.5 billion, recently executed a series of stock transactions, ...

Caption Illustration of a cardiac sarcomere, the elementary unit of cardiac muscle cells that contracts on a beat-to-beat basis. By being precisely positioned near the center of the sarcomere ...

Prolonged exposure to microgravity in space weakens the heart muscle and disrupts the heart’s rhythm, Johns Hopkins ...

Staining indicates cardiac sarcomere proteins alpha actinin and cardiac troponin T, in addition to nuclear stain DAPI. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news ...

cardiac sarcomere modulator, specifically designed to slow early contraction velocity and address impaired cardiac relaxation associated with hypertrophic cardiomyopathy (HCM) and other diseases ...

Robert Blaustein, M.D., Ph.D., joins the Company as Chief Development Officer, responsible for leading EDG-7500, a novel cardiac sarcomere modulator in Phase 2 development, as well as the ...