Pancreatic blood vessel cell map reveals potential diabetes treatment pathways
The distinct population of endothelial cells that line blood vessels in the insulin-producing "islets" of the human pancreas ...
GEN2d
Dysfunctional Mitochondria Trigger Retrograde Signaling that Impairs Pancreatic β-Cells
Targeting mitochondrial retrograde signaling may therefore be promising in the treatment or prevention of metabolic disorders ...
Gene modification can encourage T cell growth, improving cancer treatment's success rate
Researchers have identified a method to enhance the effectiveness of a promising cancer treatment. They found that modifying ...
Inability of cells to recycle fats can spell disease: Study reveals how a protein helps transport fats out of lysosomes
Accumulation of fat molecules is detrimental to the cell. Researchers from the Yong Loo Lin School of Medicine, National ...
Bacterial cellulose promotes plant tissue regeneration, study shows
A study has elucidated the mechanism by which bacterial cellulose mediates plant tissue regeneration. The work has been ...
eLife1d
Bridging the Gap in Cancer Cell Behavior Against Matrix Stiffening: Insights from a Trizonal Model
Laboratory for Research on the Structure of Matter (LRSM), University of Pennsylvania, Philadelphia, United States ...
Science Daily1d
Gene modification could improve cancer treatment's success rate
A research team has made a major discovery on how the CUL5 gene affects CAR-T cell therapy, an advanced cancer therapy. The study reveals that reducing the activity of the CUL5 gene helps CAR-T cells ...
Science Daily8d
Outside-in signaling shows a route into cancer cells
A new study shows how an anticancer drug triggers an 'outside in' signal that gets it sucked into a cancer cell. The work reveals a new signaling mechanism that could be exploited for delivering other ...
eLife9d
Single-cell sequencing provides clues about the developmental genetic basis of evolutionary adaptations in syngnathid fishes
This study provides a valuable new resource to investigate the molecular basis of the particular features characterizing the pipefish embryo. The authors found both unique and shared gene expression ...