Safeguarding intestinal stem cells during aging through balanced signaling
A recent study led by Associate Professor Takuya Yamamoto and Researcher May Nakajima-Koyama has revealed that maintaining a ...
The Scientist3d
Understanding the Cellular Landscape that Fuels Endometriosis
Profiling cells from ovarian endometriosis revealed signaling interactions that may sustain legion growth, highlighting ...
News Medical on MSN2d
Single-cell transcriptome profiling identifies the activation of type I interferon signaling in ossified posterior longitudinal ligament
Ossification of the posterior longitudinal ligament (OPLL) is a progressive spinal disease characterized by ectopic bone ...
Study identifies potential role of interferon signaling in progressive spinal disease
Ossification of the posterior longitudinal ligament (OPLL) is a progressive spinal disease characterized by ectopic bone ...
Science Daily4d
Gene modification could improve cancer treatment's success rate
A research team has made a major discovery on how the CUL5 gene affects CAR-T cell therapy, an advanced cancer therapy. The study reveals that reducing the activity of the CUL5 gene helps CAR-T cells ...
Armed robbery in Revesby11d
Outside-In Signaling Shows Route Into Cancer Cells
A new study shows how an anticancer drug triggers an "outside in" signal that gets it sucked into a cancer cell. The work, ...
GEN5d
Dysfunctional Mitochondria Trigger Retrograde Signaling that Impairs Pancreatic β-Cells
Targeting mitochondrial retrograde signaling may therefore be promising in the treatment or prevention of metabolic disorders ...
The EMBO Journal2d
Modulation of tumor inflammatory signaling and drug sensitivity by CMTM4
Despite the established links between inflammation and cancer development, the effects of inflammatory signaling on cancer ...
eLife12d
Single-cell sequencing provides clues about the developmental genetic basis of evolutionary adaptations in syngnathid fishes
This study provides a valuable new resource to investigate the molecular basis of the particular features characterizing the pipefish embryo. The authors found both unique and shared gene expression ...
Science Daily11d
Outside-in signaling shows a route into cancer cells
A new study shows how an anticancer drug triggers an 'outside in' signal that gets it sucked into a cancer cell. The work reveals a new signaling mechanism that could be exploited for delivering other ...