Engineered immune cells called CAR-T cells are used in the treatment of cancer. Researchers from Uppsala University have now ...
Pharmaceutical ads are difficult to avoid in American television programming and a growing number of them promote a class of ...
The pre-B-cell receptor (pre-BCR), which comprises two Igμ chains and two germline-encoded surrogate light chains (SLC) that are associated with the signalling subunits Igα and Igβ, is formed ...
to target a cell-surface receptor called DR5 (death receptor 5) that many tumor cells have. When activated, DR5 can trigger the death of these cells by a self-destruct process called apoptosis.
Chimeric antigen receptor-T (CAR-T) cell therapy ... 37 Natural killer group 2 member D ligands are stress-induced molecules expressed on the surface of tumor cells, including CRC. 43 Targeting them ...
AstraZeneca and Daiichi Sankyo’s Enhertu (trastuzumab deruxtecan) has been approved in the US for the treatment of adult patients with unresectable or metastatic hormone receptor (HR)-positive, ...
T lymphocytes are important mediators of adoptive immunity but the mechanism of T cell receptor ... segregation of receptor protein tyrosine phosphatases from engaged TCRs may be a result of ...
Toll-like receptors (TLRs ... 1 TLR signaling pathway in innate immune cells. TLR5, TLR4, and the heterodimers of TLR2–TLR1 or TLR2–TLR6 prefer to recognize the membrane components of pathogens at the ...
The Sudan virus, a close relative of Ebola, has a fatality rate of 50% but remains poorly understood in terms of how it infects cells. Currently, no approved treatments exist.
A new publication from Opto-Electronic Advances; DOI 10.29026/oea.2025.240152, discusses how multi-photon bionic skin ...