The Falke group is currently investigating the molecular mechanisms of on-off switching of components within the chemosensory array, especially the mechanisms by which transmembrane receptors bind ...

Cheng et al. have now designed autophagy-inducing antibodies (AUTABs) that promote internalization and lysosomal degradation of their target cell surface receptor through autophagy. Autophagy ...

CD14 and the Fcγ receptors CD32 and CD64 belong to a group of cell surface receptors engaged in phagocytosis by various types of phagocytes, including macrophages, dendritic cells and monocytes 14.