Although the pathogenesis of DKA is better understood than that of HHS, the basic underlying mechanism for both disorders is a reduction in the net effective concentration of circulating insulin ...

Seek emergency medical attention if you experience any symptoms of DKA or HHS. Other complications of mismanaged hyperglycemia tend to take a lot longer to develop but are just as serious.

Diabetic ketoacidosis occurs when your body doesn’t make enough insulin to process the glucose in your blood. This leads to very high blood glucose levels, which can cause many complications.

In the present proposed protocol, we have used essentially the same insulin regimen for both DKA and HHS, but because of a greater level of mental obtundation in HHS, we have recommended only ...