Here, our current understanding of the MAP kinase pathway is reviewed, as well as recent advances in the design of novel agents that are able to modulate the activity of these signalling cascades.

Notably, core components in the ufmylation cascade, Ufl1 and Ufm1, interact with the autophagy kinase complexes proteins ATG1 and ATG6. Cellular and genetic analysis showed that Ufl1 is important for ...

Living matter remains the quintessential puzzle of biological sciences, a question that embodies the intricate complexity and stunning diversity of life forms. A new study suggests that one viable ...

MAPK cascades respond to various environmental stress factors by modulating associated gene expression, influencing plant hormone synthesis, and facilitating interactions with other environmental ...

Karlstrom — along with researchers from Oregon State University, Duke and the U.S. Forest Service — are trying to map out how much water is stored beneath the volcanic rocks of the Cascades.

The two researchers were describing a massive storehouse of water buried below Oregon’s Central Cascade Mountains that could define the state's future in a world with ever-growing thirst.

scientists say it’s possible the holes aren’t providing a complete map. They say the actual volume of water under the Cascades may be even bigger than three Lake Meads. Scientists caution ...