This study is the first to demonstrate that certain tRNA introns influence gene expression. Scientists have discovered that ...

By treating DNA as a language, Brian Hie’s “ChatGPT for genomes” could pick up patterns that humans can’t see, accelerating ...

RNA-based medicines are one of the most promising ways to fight human disease, as demonstrated by the recent successes of RNA ...

UMD researchers have discovered key mechanisms in gene regulation that could improve the design of RNA-based medicines.

This is where DNA and RNA epigenetics comes in: a series of mechanisms that act as "markers" on genes, to control their activity without modifying the DNA or RNA sequence itself. Until now, DNA and ...

There are many molecules with therapeutic potential, but it can be a challenge to deliver them to the right places at the ...

R-loops can help to turn on specific genes by forming an RNA:DNA "sandwich" in regulatory regions of a target gene. In the case of the NPAS4 gene, R-loops appear to help to bring the enhancer ...

Researchers studying gene expression have access to vast amounts of data from cells or tissues. This is thanks to advances in ...

A new study published in the journal eLife on February 4, 2025, may lead to breakthroughs in RNA-based drug development.