DNA integrity is always under attack from environmental ... During photoreactivation, an enzyme called photolyase binds pyrimidine dimer lesions; in addition, a second molecule known as ...

Although not directly related to thymine, 5mC is often referred to as the "fifth base" of DNA due to its significant biological role. Exposure to ultraviolet (UV) radiation can cause the formation of ...

Abbreviations: cis-Pt and MMC, cisplatin and mitomycin C, respectively (both DNA-cross-linking agents); (6–4)PP and CPD, 6–4 photoproduct and cyclobutane pyrimidine dimer, respectively (both ...

1). We have used replication systems reconstituted with purified E. coli replication proteins and DNA templates carrying a single, site-specific cyclopyrimidine dimer (CPD) to analyze the events that ...

View Full Profile. Learn about our Editorial Policies. Polymerase chain reaction (PCR) is a fundamental molecular biology tool that scientists use to amplify and analyze genetic material, such as DNA ...