For example, MEK1/2 appears to stabilize mature desmosomes but is less important for the regulation of cytoskeletal anchorage of desmosomes. In contrast, we conclude that both Src and cAMP most likely ...

Pemphigus group diseases are characterized by IgG autoantibodies directed against epidermal adhesion complexes (desmosomes) of keratinocytes ... therapy in pemphigus includes prohibitive costs. For ...

Here, we aim to define the cellular and molecular basis of collective migration using the best-studied examples, and discriminate it from other similar but mechanistically distinct types of cell ...

Pemphigus is an autoimmune bullous disease, in which autoantibodies react with the cell–cell adhesion structures, desmosomes, causing blisters and erosions on the oral mucosa and skin.

Figure 2 provides a birds-eye view of the current and future trends in the management of severe OSD. Current management may not completely restore the functions and structure of the ocular surface ...

However, did you know a lot of the bots you have been using are actually examples of artificial intelligence? The bot has been designed to mimic human-like responses and perform a variety of tasks.

This guide explains why career goals matter, provides practical examples, and offers strategies for achieving them effectively. Establishing career goals brings clarity and purpose to our professional ...

In a dark coincidence, the researchers point to California's current catastrophe as a timely example of their recently published findings. "In that publication, fairly incredibly, we use the example ...

Autoimmune disorders occur when immune cells go wrong and attack the body’s own tissues. Currently, autoimmune disorders are largely treated by broad immunosuppressive agents and blocking antibodies, ...

The term dilated cardiomyopathy (DCM) refers to a spectrum of heterogeneous myocardial disorders that are characterized by ventricular dilation and depressed myocardial performance in the absence of ...